circRNA basic information
circBase ID: hsa_circ_0070441
Name: -
Synonym: circ_0070441
Host Gene: hsa-miR-626
 
 
 
Disease basic information
DO ID:
 14330
DO name: Parkinson disease
Disease details: Parkinson disease
Species: human
Species details: human
Sample type: cell line
Sample type details: SH-SY5Y cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IRS2
Associated microRNA: hsa-miR-626
Biological function: Depletion of circ_0070441 alleviated MPP+-triggered neuronal damage by regulating cell apoptosis and inflammation.
Molecular mechanism: Circ_0070441 acted as a sponge for miR-626, and IRS2 was a target of miR-626.
Survival: -
Supported No.:
 1
Description:

circ_0070441 aggravated MPP+-triggered neurotoxic effect in SH-SY5Y cells by regulating miR-626/IRS2 axis.
Other information
Title:

Circular RNA circ_0070441 regulates MPP(+)-triggered neurotoxic effect in SH-SY5Y cells via miR-626/IRS2 axis.

Journal: Metab Brain Dis
Published: 2021/11/9
PubMed ID: 34748128