circRNA basic information
circBase ID: -
Name: hsa_circ_MTO1
Synonym: CircMTO1
Host Gene: hsa-miR-320a
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ATRX
Associated microRNA: hsa-miR-320a
Biological function: circMTO1 knockdown inhibited OSCC cell proliferation, migration, and invasion
Molecular mechanism: circMTO1/hsa-miR-320a/ATRX axis
Survival: -
Supported No.:
 1
Description:

circMTO1 modulates ATRX expression to accelerate OSCC progression by sponging miR-320a.
Other information
Title:

Circular RNA mitochondrial translation optimization 1 homologue (CircMTO1) induced by zinc finger protein 460 (ZNF460) promotes oral squamous cell carcinoma progression through the microRNA miR-320a / alpha thalassemia/mental retardation, X-linked (ATRX) axis.

Journal: Bioengineered
Published: 2021/11/6
PubMed ID: 34738503