circRNA basic information
circBase ID: hsa_circ_0058106
Name: -
Synonym: circ_0058106
Host Gene: hsa-miR-153
 
 
 
Disease basic information
DO ID:
2600
DO name: laryngeal carcinoma
Disease details: laryngeal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Twist1
Associated microRNA: hsa-miR-153
Biological function: Stable knockdown of hsa-circ_0058106 inhibited the migration and invasion of laryngeal cancer cells in vitro and in vivo
Molecular mechanism: hsa-circ_0058106 can specifically bind to hsa-miR-153 and regulate Snail1 expression by acting as a hsa-miR-153 sponge
Survival: poor
Supported No.:
1
Description:

hsa-circ_0058106 induces EMT and metastasis in laryngeal cancer by sponging miR-153 and inducing Twist1 nuclear translocation.

Other information
Title:

Hsa-circ_0058106 induces EMT and metastasis in laryngeal cancer via sponging miR-153 and inducing Twist1 nuclear translocation.

Journal: Cell Oncol (Dordr)
Published: 2021/11/6
PubMed ID: 34738200