circRNA basic information
circBase ID: -
Name: hsa_circ_ADARB1
Synonym: CircADARB1
Host Gene: -
 
 
 
Disease basic information
DO ID:
 50743
DO name: mature T-cell and NK-cell lymphoma
Disease details: natural killer/T-cell lymphoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: knockdown of circADARB1 inhibited proliferation of NKTCL cells
Molecular mechanism: CircADARB1 bound up to hsa-miR-214-3p and regulated p-Stat3
Survival: -
Supported No.:
 1
Description:

The knockdown of circADARB1 inhibited proliferation of NKTCL cells in vitro and in vivo. CircADARB1 could bind to miR-214-3p in the downstream and regulate the expression of p-Stat3.
Other information
Title:

CircADARB1 serves as a new biomarker in natural killer T-cell lymphoma and a potential regulator of p-Stat3.

Journal: Cancer Cell Int
Published: 2021/11/6
PubMed ID: 34736477