circRNA basic information
circBase ID:
-
Name:
hsa_circ_SMAD2
Synonym:
circSMAD2
Host Gene:
-
Disease basic information
DO ID:
3121
DO name:
gallbladder cancer
Disease details:
gallbladder cancer
Species:
human
Species details:
human
Sample type:
cell line, PDX
Sample type details:
-
circRNA-disease information
Detected method:
Q
Detected method confidence
High
Expression pattern:
UP
Associated gene:
eIF4A3
Associated microRNA:
-
Biological function:
circSMAD2 knockdown significantly inhibited the viability of GBC cells. In addition, circSMAD2 siRNA notably induced the apoptosis in GBC cells
Molecular mechanism:
through binding with eIF4A3
Survival:
-
Supported No.:
1
Description:
Knockdown of circSMAD2 inhibits the tumorigenesis of gallbladder cancer through binding with eIF4A3.
Other information
Title:
Knockdown of circSMAD2 inhibits the tumorigenesis of gallbladder cancer through binding with eIF4A3.
Journal:
BMC Cancer
Published:
2021/11/4
PubMed ID:
34727877