circRNA basic information
circBase ID: -
Name: hsa_circ_TLK1
Synonym: circTLK1
Host Gene: hsa-miR-452-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: gliomagenesis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: glioma cell lines (T98G, LN229, CRT, U251, M059J, M059K), normal human astrocytes (NHAs), 293T cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SSR1
Associated microRNA: hsa-miR-452-5p
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

circTLK1 mediated by PBX2 activates JAK/STAT signaling to promote glioma progression through the miR-452-5p/SSR1 pathway.
Other information
Title:

PBX2-Mediated circTLK1 Activates JAK/STAT Signaling to Promote Gliomagenesis via miR-452-5p/SSR1 Axis.

Journal: Front Genet
Published: 2021/11/2
PubMed ID: 34721518