circRNA basic information
circBase ID: -
Name: hsa_circ_TNPO3
Synonym: circ-TNPO3
Host Gene: -
 
 
 
Disease basic information
DO ID:
10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: MYC and SNAIL
Associated microRNA: -
Biological function: circ-TNPO3 inhibited proliferation and migration
Molecular mechanism: by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL
Survival: -
Supported No.:
1
Description:

circ-TNPO3 acts as a protein decoy for IGF2BP3 to regulate the MYC-SNAIL axis, thereby suppressing the proliferation and metastasis of GC.

Other information
Title:

Circular RNA circ-TNPO3 suppresses metastasis of GC by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL.

Journal: Mol Ther Nucleic Acids
Published: 2021/10/28
PubMed ID: 34703650