circRNA basic information
circBase ID: -
Name: hsa_circ_CNOT2
Synonym: CircCNOT2
Host Gene: hsa-miR-409-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal breast epithelial cell line (MCF-10A), human BC cell lines (MCF-7, SKBR-3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TWIST1
Associated microRNA: hsa-miR-409-3p
Biological function: overexpression of circCNOT2 or TWIST1 accelerated BC invasion, migration and EMT
Molecular mechanism: via regulating the hsa-miR-409-3p/TWIST1 axis
Survival: poor
Supported No.:
 2
Description:

Circular RNA CNOT2 knockdown regulates twist family BHLH transcription factor via targeting microRNA 409-3p to prevent breast cancer invasion, migration and epithelial-mesenchymal transition.
Other information
Title:

Circular RNA CNOT2 knockdown regulates twist family BHLH transcription factor via targeting microRNA 409-3p to prevent breast cancer invasion, migration and epithelial-mesenchymal transition.

Journal: Bioengineered
Published: 2021/10/27
PubMed ID: 34698000