circRNA basic information
circBase ID: -
Name: hsa_circ_PRKCI
Synonym: circPRKCI
Host Gene: hsa-miR-20a-5p
 
 
 
Disease basic information
DO ID:
 5603
DO name: T-cell acute lymphoblastic leukemia
Disease details: T-cell acute lymphoblastic leukemia
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX4
Associated microRNA: hsa-miR-20a-5p
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

we concluded that circular RNA circPRKCI contributed to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis. Targeting circPRKCI may serve as a promising therapeutic strategy of T-ALL.
Other information
Title:

Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis.

Journal: Aging (Albany NY)
Published: 2021/10/26
PubMed ID: 34695805