circRNA basic information
circBase ID: -
Name: hsa_circ_Serpine2
Synonym: circ-Serpine2
Host Gene: hsa-miR-124-3p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: KIF20A
Associated microRNA: hsa-miR-124-3p
Biological function: promot cell proliferation, migration and invasion, inhibit glioma cell apoptosis
Molecular mechanism: circ-Serpine2 could upregulate KIF20A by sponging hsa-miR-124-3p
Survival: -
Supported No.:
 1
Description:

Circ-Serpine2 exacerbated the malignant progression of glioma mediated by the miR-124-3p/KIF20A nexus.
Other information
Title:

Bioinformatics analysis reveals a stem cell-expressed circ-Serpine2-mediated miRNA-mRNA regulatory subnetwork in the malignant progression of glioma.

Journal: J Transl Med
Published: 2021/10/26
PubMed ID: 34689806