circRNA basic information
circBase ID: -
Name: hsa_circ_SIRT1
Synonym: circ-SIRT1
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EIF4A3/N-cadherin/vimentin
Associated microRNA: -
Biological function: Knocking down circ-SIRT1 inhibited the proliferation and invasion of CRC cells and EMT
Molecular mechanism: through the circ-SIRT1/EIF4A3/N-cadherin/vimentin pathway
Survival: poor
Supported No.:
 1
Description:

circ-SIRT1 functions as an oncogene in CRC by promoting the proliferation, invasion, and EMT of CRC cells through the circ-SIRT1/EIF4A3/N-cadherin/vimentin pathway.
Other information
Title:

circ-SIRT1 Promotes Colorectal Cancer Proliferation and EMT by Recruiting and Binding to eIF4A3.

Journal: Anal Cell Pathol (Amst)
Published: 2021/10/19
PubMed ID: 34660182