circRNA basic information
circBase ID: -
Name: hsa_circ_FAM160A2
Synonym: circFAM160A2
Host Gene: hsa-miR-505-3p
 
 
 
Disease basic information
DO ID:
 8398
DO name: osteoarthritis
Disease details: osteoarthritis
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: SIRT3
Associated microRNA: hsa-miR-505-3p
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

circFAM160A2 can promote mitochondrial stabilization and apoptosis reduction in OA chondrocytes by targeting miR-505-3p and SIRT3, which might be a potential therapeutic target for OA therapy.
Other information
Title:

circFAM160A2 Promotes Mitochondrial Stabilization and Apoptosis Reduction in Osteoarthritis Chondrocytes by Targeting miR-505-3p and SIRT3.

Journal: Oxid Med Cell Longev
Published: 2021/10/15
PubMed ID: 34646424