circRNA basic information
circBase ID: hsa_circ_0002483
Name: hsa_circ_PTK2
Synonym: -
Host Gene: hsa-miR-125a-3p
 
 
 
Disease basic information
DO ID:
 3910
DO name: lung adenocarcinoma
Disease details: lung adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A549, PC9 cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCL4-CCR5
Associated microRNA: hsa-miR-125a-3p
Biological function: Knockdown of circ_0002483 inhibited proliferation, colony formation and invasion
Molecular mechanism: miRNA sponge
Survival: better
Supported No.:
 1
Description:

circ_0002483 could act as a sponge of miR-125a-3p to upregulate CCL4-CCR5 axis, contributing to the tumorigenesis of LUAC, and represent a potential therapeutic target for LUAC.
Other information
Title:

Circular RNA hsa_circ_0002483 promotes growth and invasion of lung adenocarcinoma by sponging miR-125a-3p.

Journal: Cancer Cell Int
Published: 2021/10/14
PubMed ID: 34641879