circRNA basic information
circBase ID: hsa_circ_0075804
Name: -
Synonym: Circ_0075804
Host Gene: hsa-miR-138-5p
 
 
 
Disease basic information
DO ID:
 768
DO name: retinoblastoma
Disease details: retinoblastoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: RB cell lines (Y79, WERI-Rb-1, HXO-Rb44), human retinal pigment epithelial cell line (ARPE-19)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PEG10
Associated microRNA: hsa-miR-138-5p
Biological function: Circ_0075804 knockdown restrained the proliferation, migration and invasion whereas promoted the apoptosis of RB cells
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 3
Description:

Circ_0075804 promoted RB progression via miR-138-5p-dependent regulation of PEG10.
Other information
Title:

Circ_0075804 promotes the malignant behaviors of retinoblastoma cells by binding to miR-138-5p to induce PEG10 expression.

Journal: Int Ophthalmol
Published: 2021/10/12
PubMed ID: 34633608