circRNA basic information
circBase ID: -
Name: hsa_circ_WHSC1
Synonym: CircWHSC1
Host Gene: hsa-miR-212-5p
 
 
 
Disease basic information
DO ID:
 60081
DO name: triple-receptor negative breast cancer
Disease details: triple-negative breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: AKT3
Associated microRNA: hsa-miR-212-5p
Biological function: CircWHSC1 silencing reduced TNBC cell growth in vivo and repressed proliferation, migration, invasion, glycolysis, and induced apoptosis of TNBC cells in vitro
Molecular mechanism: CircWHSC1 regulated AKT3 expression by sponging hsa-miR-212-5p
Survival: poor
Supported No.:
 1
Description:

CircWHSC1 accelerated malignancy and glycolysis of TNBC cells by the miR-212-5p/AKT3 axis.
Other information
Title:

CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer.

Journal: Exp Mol Pathol
Published: 2021/10/9
PubMed ID: 34624276