circRNA basic information
circBase ID: -
Name: hsa_circ_DTL
Synonym: CircDTL
Host Gene: hsa-miR-1287-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GPX4
Associated microRNA: hsa-miR-1287-5p
Biological function: Knockdown of circDTL promoted both apoptosis and ferroptosis of NSCLC cells
Molecular mechanism: via the circDTL/hsa-miR-1287-5p/GPX4 axis
Survival: -
Supported No.:
 1
Description:

CircDTL acts as an oncogene and exerts its effects via the miR-1287-5p/GPX4 axis in NSCLC.
Other information
Title:

CircDTL Functions as an Oncogene and Regulates Both Apoptosis and Ferroptosis in Non-small Cell Lung Cancer Cells.

Journal: Front Genet
Published: 2021/10/9
PubMed ID: 34621297