circRNA basic information
circBase ID: -
Name: hsa_circ_HN1
Synonym: circ-HN1
Host Gene: hsa-miR-485-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: GSK3A
Associated microRNA: hsa-miR-485-5p
Biological function: promote cell proliferation, migration, and invasion
Molecular mechanism: circ-HN1-hsa-miR-485-5p-GSK3A regulatory network
Survival: -
Supported No.:
 4
Description:

silencing of the circ-HN1-miR-485-5p-GSK3A regulatory network inhibited GC cell proliferation, migration, and invasion, suggesting that circ-HN1 is a potential target for GC therapy.
Other information
Title:

Downregulation of circular RNA circ-HN1 suppressed the progression of gastric cancer through the miR-485-5p/GSK3A pathway.

Journal: Bioengineered
Published: 2021/10/6
PubMed ID: 34607506