circRNA basic information
circBase ID: -
Name: hsa_circ_RPPH1
Synonym: Circ-RPPH1
Host Gene: hsa-miR-328-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGA2
Associated microRNA: hsa-miR-328-3p
Biological function: Circ-RPPH1 knockdown or miR-328-3p re-expression suppressed cell proliferation, migration, invasion and glycolysis but induced apoptosis in BC in vitro.
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 9
Description:

Circ-RPPH1 knockdown retarded cell malignant phenotypes and glycolysis via miR-328-3p/HMGA2 axis in BC, providing a potential therapeutic target for BC treatment.
Other information
Title:

Circ-RPPH1 knockdown retards breast cancer progression via miR-328-3p-mediated suppression of HMGA2.

Journal: Clin Breast Cancer
Published: 2021/10/2
PubMed ID: 34593318