circRNA basic information
circBase ID: hsa_circ_0058493
Name: hsa_circ_RHBDD1
Synonym: -
Host Gene: hsa-miR-548b-3p
 
 
 
Disease basic information
DO ID:
 8552
DO name: chronic myeloid leukemia
Disease details: chronic myeloid leukemia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-548b-3p
Biological function: Silencing the expression of circ_0058493 significantly inhibited the development of imatinib-resistant CML cells
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Hsa_circ_0058493 was significantly overexpressed in the PBMCs of CML patients and high level of circ_0058493 was associated with the poor clinical efficacy of imatinib.
Other information
Title:

CircRNA Microarray Profiling Reveals hsa_circ_0058493 as a Novel Biomarker for Imatinib-Resistant CML.

Journal: Front Pharmacol
Published: 2021/10/1
PubMed ID: 34588984