circRNA basic information
circBase ID: hsa_circ_0001821
Name: -
Synonym: circ_0001821
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9538
DO name: multiple myeloma
Disease details: multiple myeloma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Caspase-3
Associated microRNA: -
Biological function: Overexpression of circ_0001821 led to increased proliferation and arrested apoptosis of multiple myeloma cells, while knockdown of circ_0001821 had the opposite effects
Molecular mechanism: -
Survival: poor
Supported No.:
 1
Description:

High expression of circ_0001821 associated with aggressive pathological indicators and predicted a poor prognosis in multiple myeloma. Circ_0001821 played an oncogenic role in multiple myeloma by modulating cell proliferation and apoptosis.
Other information
Title:

CircRNA circ_0001821 predicts an unfavorable prognosis and promotes the proliferation of multiple myeloma.

Journal: Hematology
Published: 2021/9/24
PubMed ID: 34555307