circRNA basic information
circBase ID: -
Name: hsa_circ_DNA2
Synonym: circDNA2
Host Gene: hsa-miR-149-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CCDC6
Associated microRNA: hsa-miR-149-5p
Biological function: Knockdown of circDNA2 expression suppressed the proliferation of GC cells by reducing CCDC6 expression
Molecular mechanism: circDNA2 acted as a microRNA (miR)-149-5p sponge, which was confirmed to target CCDC6
Survival: poor
Supported No.:
 2
Description:

circDNA2 contributes to the growth and lymphatic metastasis of GC by upregulating CCDC6 expression by sponging miR-149-5p.
Other information
Title:

Circular RNA circDNA2 upregulates CCDC6 expression to promote the progression of gastric cancer via miR-149-5p suppression.

Journal: Mol Ther Nucleic Acids
Published: 2021/9/24
PubMed ID: 34552818