circRNA basic information
circBase ID: hsa_circ_0002874
Name: hsa_circ_GLIS3
Synonym: CircGLIS3
Host Gene: -
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: high-grade glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: Ezrin T567
Associated microRNA: -
Biological function: upregulation of circGLIS3 promoted glioma cell migration and invasion and showed aggressive characteristics in tumor-bearing mice
Molecular mechanism: circGLIS3 could promote the Ezrin T567 phosphorylation level
Survival: -
Supported No.:
 2
Description:

circGLIS3 is upregulated in high-grade glioma and contributes to the invasion and angiogenesis of glioma via modulating Ezrin T567 phosphorylation.
Other information
Title:

CircGLIS3 Promotes High-Grade Glioma Invasion via Modulating Ezrin Phosphorylation.

Journal: Front Cell Dev Biol
Published: 2021/9/21
PubMed ID: 34540823