circRNA basic information
circBase ID: -
Name: hsa_circ_POLA2
Synonym: -
Host Gene: hsa-miR-31
 
 
 
Disease basic information
DO ID:
 1380
DO name: endometrial cancer
Disease details: endometrial cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-31
Biological function: circ_POLA2 overexpression also increased EC cell proliferation, while miR-31 overexpression decreased cell proliferation
Molecular mechanism: increases microRNA-31 methylation
Survival: -
Supported No.:
 1
Description:

circ_POLA2 may increase miR-31 methylation of miR-31 in EC cells to promote cancer cell proliferation.
Other information
Title:

circRNA circ_POLA2 increases microRNA-31 methylation to promote endometrial cancer cell proliferation.

Journal: Oncol Lett
Published: 2021/9/21
PubMed ID: 34539866