circRNA basic information
circBase ID: -
Name: hsa_circ_NCKAP1
Synonym: Circ_NCKAP1
Host Gene: hsa-miR-148b-5p
 
 
 
Disease basic information
DO ID:
 2513
DO name: basal cell carcinoma
Disease details: skin basal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: HSP90
Associated microRNA: hsa-miR-148b-5p
Biological function: circ_NCKAP1 knockdown markedly inhibited cell proliferation and promoted cell apoptosis (p<0.05)
Molecular mechanism: by sponging the hsa-miR-148b-5p/HSP90 axis
Survival: -
Supported No.:
 1
Description:

Circ_NCKAP1 can promote skin BCC progression by sponging the miR-148b-5p/HSP90 axis, and circ_NCKAP1 may be a potential target for skin BCC therapy.
Other information
Title:

Circ_NCKAP1 promotes skin basal cell carcinoma progression by sponging the miR-148b-5p/HSP90 axis.

Journal: Eur Rev Med Pharmacol Sci
Published: 2021/9/18
PubMed ID: 34533810