circRNA basic information
circBase ID: -
Name: hsa_circ_PTCH1
Synonym: CircPTCH1
Host Gene: hsa-miR-34c-5p
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BEAS-2B, A549, NCI-H1299, SK-MES-1, NCI-H661
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: MYCN
Associated microRNA: hsa-miR-34c-5p
Biological function: circPTCH1 reduced lung cancer cells migration and invasion
Molecular mechanism: by targeting the hsa-miR-34c-5p/MYCN axis
Survival: -
Supported No.:
 1
Description:

circPTCH1 plays a tumor enhancement role in lung cancer and that can effectively promote migration, invasion and EMT by targeting the miR-34c-5p/MYCN axis.
Other information
Title:

CircPTCH1 Promotes Migration in Lung Cancer by Regulating MYCN Expression Through miR-34c-5p.

Journal: Onco Targets Ther
Published: 2021/9/18
PubMed ID: 34531664