circRNA basic information
circBase ID: -
Name: hsa_circ_SFMBT2
Synonym: Circ-SFMBT2
Host Gene: hsa-miR-107
 
 
 
Disease basic information
DO ID:
 5041
DO name: esophageal cancer
Disease details: esophageal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SLC1A5
Associated microRNA: hsa-miR-107
Biological function: Circ-SFMBT2 downregulation inhibited EC cell proliferation, invasion and glutamine metabolism.
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

circ-SFMBT2 upregulated the SLC1A5 expression to promote the malignant development of EC by serving as a miR-107 sponge.
Other information
Title:

Circ-SFMBT2 drives the malignant phenotypes of esophageal cancer by the miR-107-dependent regulation of SLC1A5.

Journal: Cancer Cell Int
Published: 2021/9/18
PubMed ID: 34530825