circRNA basic information
circBase ID: hsa_circ_0026552
Name: hsa_circ_IGFBP6
Synonym: -
Host Gene: hsa-miR-331-3p
 
 
 
Disease basic information
DO ID:
 10591
DO name: pre-eclampsia
Disease details: preeclampsia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: trophoblastic HTR_8/SVneo cells
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: TGF_betaR1
Associated microRNA: hsa-miR-331-3p
Biological function: silencing hsa_circ_0026552 could significantly strengthen the proliferation, migration and invasion of the trophoblastic HTR_8/SVneo cells
Molecular mechanism: hsa_circ_0026552 acts as a miR_331_3p sponge to upregulate TGF_betaR1 expression in trophoblasts and is involved significantly in PE development and progression in pregnant women.
Survival: -
Supported No.:
 1
Description:

Circular RNA hsa_circ_0026552 inhibits the proliferation, migration and invasion of trophoblast cells via the miR_331_3p/TGF_betaR1 axis in pre_eclampsia.
Other information
Title:

Circular RNA hsa_circ_0026552 inhibits the proliferation, migration and invasion of trophoblast cells via the miR_331_3p/TGF_betaR1 axis in pre_eclampsia.

Journal: Mol Med Rep
Published: 2021/9/16
PubMed ID: 34523694