circRNA basic information
circBase ID: hsa_circ_0000677
Name: -
Synonym: circ_0000677
Host Gene: hsa-miR-106b
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human NSCLC lines (NCI-H358, NCI-H1650, NCI-H1568, HCC827, A549, NCI-H1299)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCND1
Associated microRNA: hsa-miR-106b
Biological function: circ_0000677 knockdown markedly inhibited proliferation of NSCLC cells
Molecular mechanism: circ_0000677 acted as a sponge of microRNA-106b and further regulated CCDND1 gene expression in NSCLC cells
Survival: poor
Supported No.:
 1
Description:

Circular RNA Circ_0000677 promotes cell proliferation by regulating microRNA-106b-5p/CCND1 in non-small cell lung cancer.
Other information
Title:

Circular RNA Circ_0000677 promotes cell proliferation by regulating microRNA-106b-5p/CCND1 in non-small cell lung cancer.

Journal: Bioengineered
Published: 2021/9/15
PubMed ID: 34519258