circRNA basic information
circBase ID: -
Name: rno_circ_SMEK1
Synonym: circSMEK1
Host Gene: rno-miR-216a-5p
 
 
 
Disease basic information
DO ID:
 936
DO name: brain disease
Disease details: neuropathic pain
Species: rat
Species details: rat
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TXNIP
Associated microRNA: rno-miR-216a-5p
Biological function: -
Molecular mechanism: circSMEK1 mediated TXNIP expression through competitive adsorption of miR-216a-5p
Survival: -
Supported No.:
 1
Description:

circSMEK1 facilitates NP inflammation and microglia M1 polarization by modulating miR-216a-5p/TXNIP axis.
Other information
Title:

Circular RNA SMEK1 promotes neuropathic pain in rats through targeting microRNA-216a-5p to mediate Thioredoxin Interacting Protein (TXNIP) expression.

Journal: Bioengineered
Published: 2021/9/15
PubMed ID: 34517790