circRNA basic information
circBase ID: hsa_circ_0005654
Name: -
Synonym: circ0005654
Host Gene: hsa-miR-363
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: sp1
Associated microRNA: hsa-miR-363
Biological function: silencing of circ0005654 remarkably suppressed GC cell proliferation, migration and invasiveness in vitro and tumorigenesis and metastases in vivo
Molecular mechanism: circ0005654 served as a hsa-miR-363 sponge and enhanced sp1 expression.
Survival: poor
Supported No.:
 2
Description:

circ0005654 expedites the GC development via miR-363/sp1/myc/Wnt/beta-catenin axis and is a new biomarker for GC treatment regimen.
Other information
Title:

The circular RNA circ0005654 interacts with specificity protein 1 via microRNA-363 sequestration to promote gastric cancer progression.

Journal: Bioengineered
Published: 2021/9/10
PubMed ID: 34499009