circRNA basic information
circBase ID: -
Name: hsa_circ_FADS2
Synonym: circFADS2
Host Gene: hsa-miR-643
 
 
 
Disease basic information
DO ID:
 1002
DO name: endometritis
Disease details: endometritis
Species: human
Species details: human
Sample type: cell line
Sample type details: HEnEpC
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-643
Biological function: Cell apoptosis analysis showed that circFADS2 and miR-643 overexpression protected HEnEpCs from LPS-induced cell apoptosis, and miR-643 inhibition reduced the effect of circFADS2 overexpression.
Molecular mechanism: CircFADS2 overexpression in HEnEpCs increased the level of mature miR-643 but not premature miR-643.
Survival: -
Supported No.:
 1
Description:

CircFADS2 is downregulated in endometritis, and it overexpression promotes miR-643 maturation in HEnEpCs to suppress cell apoptosis.
Other information
Title:

CircRNA circFADS2 is Downregulated in Endometritis and its Overexpression Promotes miR-643 Maturation in Human Endometrial Epithelial Cells to Suppress Cell Apoptosis.

Journal: Reprod Sci
Published: 2021/9/4
PubMed ID: 34478121