circRNA basic information
circBase ID: hsa_circ_0001982
Name: hsa_circ_RNF111
Synonym: -
Host Gene: hsa-miR-143
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human breast epithelial cell (HBL-100), human breast cancer cell lines (MDA-MB-231, MCF-7, MDAMB-468, MDA-MB-435s)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-143
Biological function: promote proliferation and invasion
Molecular mechanism: targeting hsa-miR-143
Survival: -
Supported No.:
 2
Description:

Loss-of-function and rescue experiments revealed that hsa_circ_0001982 knockdown suppressed breast cancer cell proliferation and invasion and induced apoptosis by targeting miR-143.
Other information
Title:

Circular RNA hsa_circ_0001982 Promotes Breast Cancer Cell Carcinogenesis Through Decreasing miR-143.

Journal: DNA Cell Biol
Published: 2017/9/22
PubMed ID: 28933584