circRNA basic information
circBase ID: -
Name: hsa_circ_PPFIA1
Synonym: circPPFIA1
Host Gene: hsa-miR-340-3p
 
 
 
Disease basic information
DO ID:
 2876
DO name: laryngeal squamous cell carcinoma
Disease details: laryngeal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: LSCC cell lines (TU212, TU177, LSC-1, TU686, AMC-HN-8)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ELK1
Associated microRNA: hsa-miR-340-3p
Biological function: circPPFIA1 knockdown can suppress the proliferation, migration, and invasion of LSCC cells, while circPPFIA1 overexpression can promote these processes
Molecular mechanism: via the hsa-miR-340-3p/ELK1 signaling axis
Survival: -
Supported No.:
 1
Description:

A novel circular RNA circPPFIA1 promotes laryngeal squamous cell carcinoma progression through sponging miR-340-3p and regulating ELK1 expression.
Other information
Title:

A novel circular RNA circPPFIA1 promotes laryngeal squamous cell carcinoma progression through sponging miR-340-3p and regulating ELK1 expression.

Journal: Bioengineered
Published: 2021/8/31
PubMed ID: 34455918