circRNA basic information
circBase ID: hsa_circ_0062270
Name: -
Synonym: Circ_0062270
Host Gene: hsa-miR-331-3p
 
 
 
Disease basic information
DO ID:
 1909
DO name: melanoma
Disease details: melanoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EPHA2
Associated microRNA: hsa-miR-331-3p
Biological function: Knockdown of circ_0062270 inhibited proliferation, promoted apoptosis, and repressed metastasis in melanoma
Molecular mechanism: through regulating the hsa-miR-331-3p/EPHA2 axis
Survival: -
Supported No.:
 2
Description:

Circ_0062270 accelerated the progression of melanoma through regulating the miR-331-3p/EPHA2 axis, suggesting that circ_0062270 might be a novel potential therapeutic target for melanoma.
Other information
Title:

Circ_0062270 upregulates EPHA2 to facilitate melanoma progression via sponging miR-331-3p.

Journal: J Dermatol Sci
Published: 2021/8/30
PubMed ID: 34454812