circRNA basic information
circBase ID: -
Name: hsa_circ_HECTD1
Synonym: -
Host Gene: hsa-miR-182-5p
 
 
 
Disease basic information
DO ID:
 8577
DO name: ulcerative colitis
Disease details: ulcerative colitis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Caco-2 cells, C57BL/6 mice
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: HuR
Associated microRNA: hsa-miR-182-5p
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Overexpression of circHECTD1 alleviates UC by promoting HuR-dependent autophagy via miR-182_5p. This study highlights the therapeutic potential of circHECTD1 for UC and adds to the knowledge of circRNA in the pathogenesis of UC.
Other information
Title:

Circular RNA HECTD1 Mitigates Ulcerative Colitis by Promoting Enterocyte Autophagy Via miR-182-5p/HuR Axis.

Journal: Inflamm Bowel Dis
Published: 2021/8/25
PubMed ID: 34427642