circRNA basic information
circBase ID: hsa_circ_0023990
Name: hsa_circ_NOX4
Synonym: -
Host Gene: hsa-miR-485-5p
 
 
 
Disease basic information
DO ID:
 3969
DO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXM1
Associated microRNA: hsa-miR-485-5p
Biological function: The higher level of hsa_circ_0023900 could stimulate the proliferation and glycolysis of dedifferentiated TC cells
Molecular mechanism: via positively regulating FOXM1
Survival: -
Supported No.:
 1
Description:

Our results discovered the functional network of hsa_circ_0023990 in dedifferentiated TC development by facilitating cell proliferation and glycolysis via miR-485-5p/FOXM1 axis, implying that hsa_circ_0023990 might be a potential therapeutic target for the dedifferentiated TC treatment.
Other information
Title:

Hsa_circ_0023990 Promotes Tumor Growth and Glycolysis in Dedifferentiated TC via Targeting miR-485-5p/FOXM1 Axis.

Journal: Endocrinology
Published: 2021/8/21
PubMed ID: 34414414