circRNA basic information
circBase ID: hsa_circ_0005909
Name: hsa_circ_XPR1
Synonym: -
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX4
Associated microRNA: hsa-miR-338-3p
Biological function: knockdown of circ_0005909 was observed to suppress the proliferation, metastasis, and drug resistance of NSCLC cells
Molecular mechanism: circ_0005909 could act as a sponge of miRNA-338-3p, and miRNA-338-3p could target SOX4
Survival: poor
Supported No.:
 1
Description:

circ_0005909 promoted the progression of NSCLC via the modulation of the miRNA-338-3p/SOX4 axis, which may be a therapeutic target for NSCLC.
Other information
Title:

circRNA hsa_circ_0005909 Predicts Poor Prognosis and Promotes the Growth, Metastasis, and Drug Resistance of Non-Small-Cell Lung Cancer via the miRNA-338-3p/SOX4 Pathway.

Journal: Dis Markers
Published: 2021/8/21
PubMed ID: 34413915