circRNA basic information
circBase ID: hsa_circ_0005379
Name: -
Synonym: circ_0005379
Host Gene: hsa-miR-17-5p
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ACOX1
Associated microRNA: hsa-miR-17-5p
Biological function: inhibit the proliferation, migration, and invasion
Molecular mechanism: by downregulating the expression of hsa-miR-17-5p and upregulating ACOX1
Survival: -
Supported No.:
 2
Description:

circ_0005379 may inhibit the proliferation, migration, and invasion of OSCC cells by downregulating the expression of miR-17-5p and upregulating ACOX1, which promote apoptosis and inhibit tumor growth in vivo. circ_0005379 may be a potential target for OSCC treatment.
Other information
Title:

circ_0005379 inhibits the progression of oral squamous cell carcinoma by regulating the miR-17-5p/acyl-CoA oxidase 1 axis.

Journal: Hua Xi Kou Qiang Yi Xue Za Zhi
Published: 2021/8/20
PubMed ID: 34409798