circRNA basic information
circBase ID: hsa_circ_0005875
Name: -
Synonym: Circ_0005875
Host Gene: hsa-miR-502-5p
 
 
 
Disease basic information
DO ID:
 4450
DO name: renal cell carcinoma
Disease details: renal cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ETS1
Associated microRNA: hsa-miR-502-5p
Biological function: Knockdown of circ_0005875 suppressed RCC cell proliferation, migration and invasion, and induced apoptosis and cell cycle arrest.
Molecular mechanism: circ_0005875 knockdown decreased ETS1 expression by sponging hsa-miR-502-5p
Survival: -
Supported No.:
 1
Description:

Circ_0005875 knockdown suppressed RCC progression by regulating miR-502-5p/ETS1 axis.
Other information
Title:

Circ_0005875 sponges miR-502-5p to promote renal cell carcinoma progression through upregulating E26 transformation specific-1.

Journal: Anticancer Drugs
Published: 2021/8/19
PubMed ID: 34407050