circRNA basic information
circBase ID: hsa_circ_0000517
Name: -
Synonym: circ_0000517
Host Gene: hsa-miR-330-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: YY1
Associated microRNA: hsa-miR-330-5p
Biological function: Silencing of circ_0000517 significantly inhibited the proliferation, glycolysis, and glutamine decomposition of NSCLC cells in vitro and repressed the growth of xenografted tumors in vivo
Molecular mechanism: through regulating hsa-miR-330-5p/YY1 axis
Survival: poor
Supported No.:
 2
Description:

silencing of circ_0000517 improved the progression of NSCLC through regulating miR-330-5p/YY1 axis.
Other information
Title:

Silencing of circ_0000517 suppresses proliferation, glycolysis, and glutamine decomposition of non-small cell lung cancer by modulating miR-330-5p/YY1 signal pathway.

Journal: Kaohsiung J Med Sci
Published: 2021/8/19
PubMed ID: 34405943