circRNA basic information
circBase ID: -
Name: hsa_circ_RPPH1
Synonym: circ_RPPH1
Host Gene: hsa-miR-542-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ARHGAP1
Associated microRNA: hsa-miR-542-3p
Biological function: circ_RPPH1 knockdown or miR-542-3p introduction inhibited BC cell proliferation and metastasis, while promoted apoptosis in vitro
Molecular mechanism: circ_RPPH1 sponged hsa-miR-542-3p to upregulate ARHGAP1 expression
Survival: -
Supported No.:
 9
Description:

circ_RPPH1 contributed to BC tumorigenesis by sponging miR-542-3p and upregulating ARHGAP1, affording a novel mechanistic pathway in BC development.
Other information
Title:

circRNA RPPH1 Facilitates the Aggravation of Breast Cancer Development by Regulating miR-542-3p/ARHGAP1 Pathway.

Journal: Cancer Biother Radiopharm
Published: 2021/8/18
PubMed ID: 34402683