circRNA basic information
circBase ID: -
Name: hsa_circ_CDYL
Synonym: circCDYL
Host Gene: hsa-miR-92b-3p
 
 
 
Disease basic information
DO ID:
 0060079
DO name: Her2-receptor positive breast cancer
Disease details: HER2-positive breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-92b-3p
Biological function: promoted proliferation
Molecular mechanism: -
Survival: poor
Supported No.:
 1
Description:

MiR-92b-3p-dependent cleavage of circCDYL was an essential mechanism in regulating cell proliferation of HER2(+) breast cancer cells. CircCDYL was proved to be a potential therapeutic target for HER2(+) breast cancer, and both circCDYL and miR-92b-3p might be potential biomarkers in predicting clinical outcome of HER2(+) breast cancer patients.
Other information
Title:

MiR-92b-3p Inhibits Proliferation of HER2-Positive Breast Cancer Cell by Targeting circCDYL.

Journal: Front Cell Dev Biol
Published: 2021/8/17
PubMed ID: 34395434