circRNA basic information
circBase ID: hsa_circ_0013958
Name: -
Synonym: Circ_0013958
Host Gene: hsa-miR-637
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PLXNB2
Associated microRNA: hsa-miR-637
Biological function: promote cell proliferation, migration, invasion
Molecular mechanism: through modulating the hsa-miR-637/PLXNB2 axis
Survival: -
Supported No.:
 2
Description:

Circ_0013958 knockdown impeded OC development through modulating the miR-637/PLXNB2 axis, highlighting a therapeutic target for OC.
Other information
Title:

Circular RNA Circ_0013958 Functions as a Tumor Promoter in Ovarian Cancer by Regulating miR-637/PLXNB2 Axis.

Journal: Front Genet
Published: 2021/8/10
PubMed ID: 34367233