circRNA basic information
circBase ID: -
Name: hsa_circ_CLIP2
Synonym: Circ_CLIP2
Host Gene: hsa-miR-195-5p
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGB3
Associated microRNA: hsa-miR-195-5p
Biological function: Silencing of Circ_CLIP2 inhibited cell proliferation, enhanced cell apoptosis and inhibited the Wnt/beta-catenin signaling pathway
Molecular mechanism: Circ_CLIP2 suppressed hsa-miR-195-5p expression by directly sponging hsa-miR-195-5p
Survival: -
Supported No.:
 3
Description:

Knockdown of Circ_CLIP2 suppresses glioma progression by targeting miR-195-5p/HMGB3 thus inhibiting Wnt/beta-catenin signaling. This study may provide potential therapeutic targets against glioma.
Other information
Title:

Circ_CLIP2 promotes glioma progression through targeting the miR-195-5p/HMGB3 axis.

Journal: J Neurooncol
Published: 2021/8/7
PubMed ID: 34357490