circRNA basic information
circBase ID: hsa_circ_0016788
Name: hsa_circ_TRIM11
Synonym: -
Host Gene: hsa-miR-506-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PARP14
Associated microRNA: hsa-miR-506-3p
Biological function: hsa_circ_0016788 deficiency inhibited cell glycolysis metabolism, cell vitality, cell proliferation, colony formation, and invasion in HCC cells whereas promoted cell apoptosis.
Molecular mechanism: hsa_circ_0016788 acted as a hsa-miR-506-3p sponge to regulate the level of PARP14
Survival: -
Supported No.:
 2
Description:

Hsa_circ_0016788 facilitates the development of HCC through increasing PARP14 expression by regulating miR-506-3p, which also offered an underlying targeted therapy for HCC treatment.
Other information
Title:

Hsa_circ_0016788 regulates hepatocellular carcinoma progression via miR-506-3p/poly-adenosine diphosphate-ribose polymerase.

Journal: J Gastroenterol Hepatol
Published: 2021/8/3
PubMed ID: 34340259