circRNA basic information
circBase ID: -
Name: hsa_circ_PVT1
Synonym: -
Host Gene: hsa-miR-21-5p
 
 
 
Disease basic information
DO ID:
 2600
DO name: laryngeal carcinoma
Disease details: laryngeal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human nasopharyngeal epithelial cells NP69, LC cells TU-212, Me-4
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: CBX4
Associated microRNA: hsa-miR-21-5p
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

Knockdown of circ_PVT1 prevented LC progression via targeting miR-21-5p/CBX4 by inhibiting wnt4/beta-catenin signal pathway, which could provide a novel therapeutic target for LC.
Other information
Title:

Knockdown of Circular RNA hsa_circ_PVT1 Inhibited Laryngeal Cancer Progression via Preventing wnt4/beta-Catenin Signaling Pathway Activation.

Journal: Front Cell Dev Biol
Published: 2021/8/3
PubMed ID: 34336825