circRNA basic information
circBase ID: -
Name: hsa_circ_SPIDR
Synonym: CircSPIDR
Host Gene: hsa-miR-431-5p
 
 
 
Disease basic information
DO ID:
 3702
DO name: cervical adenocarcinoma
Disease details: cervical adenocarcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: SORCS1 and CUBN
Associated microRNA: hsa-miR-431-5p
Biological function: reduced cell viability, inhibited colony formation and promoted apoptosis
Molecular mechanism: circSPIDR suppresses cervical adenocarcinoma by competitively binding to hsa-miR-431-5p, thus upregulating SORCS1 and CUBN
Survival: -
Supported No.:
 1
Description:

circSPIDR suppresses cervical adenocarcinoma by competitively binding to miR-431-5p, thus upregulating SORCS1 and CUBN.
Other information
Title:

CircSPIDR acts as a tumour suppressor in cervical adenocarcinoma by sponging miR-431-5p and regulating SORCS1 and CUBN expression.

Journal: Aging (Albany NY)
Published: 2021/7/31
PubMed ID: 34326275