circRNA basic information
circBase ID: hsa_circ_0000520
Name: -
Synonym: Circ_0000520
Host Gene: hsa-miR-1296
 
 
 
Disease basic information
DO ID:
 60081
DO name: triple-receptor negative breast cancer
Disease details: triple-negative breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ZFX
Associated microRNA: hsa-miR-1296
Biological function: Circ_0000520 knockdown suppressed the proliferation, migration, and invasion whereas induced the apoptosis of TNBC cells
Molecular mechanism: by binding to hsa-miR-1296 to induce ZFX expression
Survival: -
Supported No.:
 1
Description:

Circ_0000520 contributed to TNBC development by binding to miR-1296 to induce ZFX expression.
Other information
Title:

Circ_0000520 contributes to triple-negative breast cancer progression through mediating the miR-1296/ZFX axis.

Journal: Thorac Cancer
Published: 2021/7/30
PubMed ID: 34324278