circRNA basic information
circBase ID: -
Name: hsa_circ_TAF4B
Synonym: circTAF4B
Host Gene: hsa-miR-1298-5p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TGFA
Associated microRNA: hsa-miR-1298-5p
Biological function: Downregulated circTAF4B abolished the growth, metastasis and EMT process in BCa cells
Molecular mechanism: circTAF4B facilitated the expression of transforming growth factor A (TGFA) by sponging hsa-miR-1298-5p
Survival: poor
Supported No.:
 1
Description:

circTAF4B played a carcinogenic role in the growth, metastasis, and EMT process of BCa by regulating the miR-1298-5p/TGFA axis.
Other information
Title:

Circular RNA TAF4B Promotes Bladder Cancer Progression by Sponging miR-1298-5p and Regulating TGFA Expression.

Journal: Front Oncol
Published: 2021/7/30
PubMed ID: 34322376