circRNA basic information
circBase ID: -
Name: hsa_circ_FAT1
Synonym: circFAT1
Host Gene: hsa-miR-21
 
 
 
Disease basic information
DO ID:
 1380
DO name: endometrial cancer
Disease details: endometrial cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: RL95-2, HEC-1-A cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-21
Biological function: increased cell stemness
Molecular mechanism: overexpression of circFAT1 increased the expression levels of hsa-miR-21 and decreased the methylation of hsa-miR-21 gene
Survival: -
Supported No.:
 1
Description:

circFAT1 is upregulated in EC and it may increase cancer cell stemness by upregulating miR-21.
Other information
Title:

Overexpression of circRNA circFAT1 in Endometrial Cancer Cells Increases Their Stemness by Upregulating miR-21 Through Methylation.

Journal: Cancer Biother Radiopharm
Published: 2021/7/28
PubMed ID: 34314629